Pak H. Chan

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

Yibing Li, Ting‐Ting Huang, Elaine J. Carlson et al. · Nature Genetics · 1995 · 1.8K citations

Medicine, Cardiology, Genetics +10

Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke

Geoffrey T. Manley, Miki Fujimura, Tonghui Ma et al. · Nature Medicine · 2000 · 1.5K citations

Medicine, Neurology, Neuroscience +17

A tetracycline derivative, minocycline, reduces inflammation and protects against focal cerebral ischemia with a wide therapeutic window

Juha Yrjänheikki, Tiina Tikka, Riitta Keinänen et al. · Proceedings of the National Academy of Sciences · 1999 · 1K citations

Life Sciences, Neuroscience, Pharmacology +17

Attenuation of focal cerebral ischemic injury in transgenic mice overexpressing CuZn superoxide dismutase.

Hiroyuki Kinouchi, C J Epstein, Takuji Mizui et al. · Proceedings of the National Academy of Sciences · 1991 · 592 citations

Life Sciences, Neurobiology, Neuroscience +17

Human copper-zinc superoxide dismutase transgenic mice are highly resistant to reperfusion injury after focal cerebral ischemia.

Guo‐Yuan Yang, Pak H. Chan, J Chen et al. · Stroke · 1994 · 573 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14