Concepedia

Insulin signalling: the role of insulin receptor substrate 1

Susanne R. Keller, Gustav E. Lienhard

Trends in Cell Biology · 1994 · 79 citations · 51 references

DOI

Concepts

References

51

SH2 domains recognize specific phosphopeptide sequences

Cell · 1993 · 2.7K citations

, , +14

Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein

Xiao‐Jian Sun, Paul Rothenberg, C. Ronald Kahn et al. · Nature · 1991 · 1.6K citations

, , +14

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

Sean E. Egan, B.W. Giddings, Mary W. Brooks et al. · Nature · 1993 · 1.2K citations

, , +14

Phosphatidylinositol 3′‐kinase is activated by association with IRS‐1 during insulin stimulation.

Jonathan Backer, Martin G. Myers, Steven E. Shoelson et al. · The EMBO Journal · 1992 · 1K citations · Full text

, , +12

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

Maria Rozakis-Adcock, Jane McGlade, Geraldine Mbamalu et al. · Nature · 1992 · 993 citations

, , +15