Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies

Impact of excipients on the absorption of P-glycoprotein substrates in vitro and in vivo

Gilles Cornaire, John M. Woodley, P Hermann et al. · International Journal of Pharmaceutics · 2004 · 294 citations

Pharmacy, Pharmacokinetics, Pharmacology +9

In Vitro Measurement of Gastrointestinal Tissue Permeability Using a New Diffusion Cell

George M. Grass, Stephanie A. Sweetana · Pharmaceutical Research · 1988 · 248 citations

Life Sciences, Biomedical Engineering, Physiology +12

A comparison of commonly used polyethoxylated pharmaceutical excipients on their ability to inhibit P‐glycoprotein activity in vitro

Erin Hugger, Barbara Novak, Philip S. Burton et al. · Journal of Pharmaceutical Sciences · 2002 · 236 citations

Pharmacy, Pharmaceutics, Pharmacology +9

P-Glycoprotein (P-gp) Mediated Efflux in Caco-2 Cell Monolayers: The Influence of Culturing Conditions and Drug Exposure on P-gp Expression Levels

Pascale Anderle, Eva Niederer, Werner Rubas et al. · Journal of Pharmaceutical Sciences · 1998 · 230 citations

Medicine, Pharmacokinetics, Pharmacology +8

Enhanced oral bioavailability of paclitaxel in mice treated with the P-glycoprotein blocker SDZ PSC 833

Judith van Asperen, Olaf van Tellingen, Alex Sparreboom et al. · British Journal of Cancer · 1997 · 203 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +9