Clinical study and stability assessment of a novel transcutaneous influenza vaccination using a dissolving microneedle patch

Sachiko Hirobe, Hiroaki Azukizawa, Takaaki Hanafusa, +6

Biomaterials

VaccinationMicroneedle PatchCross-protectionVaccine DevelopmentImmunology +10

New clinical diagnostic criteria for allergic bronchopulmonary aspergillosis/mycosis and its validation

Koichiro Asano, Akira Hebisawa, Takashi Ishiguro, +14

Journal of Allergy and Clinical Immunology

Chitosan capsules for colon-specific drug delivery: enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats

Hideyuki Tozaki, Tomokazu Odoriba, Naoki Okada, +6

Journal of Controlled Release

InflammationChitosan CapsulesMedicineGastroenterologyBiomedical Engineering +6

Hinge and Transmembrane Domains of Chimeric Antigen Receptor Regulate Receptor Expression and Signaling Threshold

Kento Fujiwara, Ayaka Tsunei, Hotaka Kusabuka, +3

Cells

Modulation of Intestinal P-Glycoprotein Function by Cremophor EL and Other Surfactants by an In Vitro Diffusion Chamber Method Using the Isolated Rat Intestinal Membranes

Yasushi Shono, Hisayo Nishihara, Y. Matsuda, +4

Journal of Pharmaceutical Sciences

Other SurfactantsBiochemistryMedicineMembrane TransportGlycobiology +6

The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1β production, ROS production and endosomal rupture

Tomohiro Morishige, Yasuo Yoshioka, Hiroshi Inakura, +10

Biomaterials

InflammationEngineeringSurface FunctionalizationNlrp3 InflammasomeImmunology +6

Climate seasonality limits leaf carbon assimilation and wood productivity in tropical forests

Fabien Wagner, Bruno Hérault, Damien Bonal, +100

Biogeosciences

Carbon AssimilationCarbon SequestrationEngineeringVegetation-atmosphere InteractionsForestry +11

Enhanced Permeability of Insulin across the Rat Intestinal Membrane by Various Absorption Enhancers: Their Intestinal Mucosal Toxicity and Absorption-enhancing Mechanism of n-Lauryl-β-D-maltopyranoside

Tomomi Uchiyama, Tetsuo Sugiyama, Ying-Shu Quan, +5

Journal of Pharmacy and Pharmacology

GlycobiologyGastroenterologyDigestive TractDietary FibreInsulin Signaling +14

Modulation of intestinal P-glycoprotein function by polyethylene glycols and their derivatives by in vitro transport and in situ absorption studies

Qi Shen, Yulian Lin, Takahiro Handa, +6

International Journal of Pharmaceutics

BiochemistryVitro TransportMedicineGlycobiologyGastroenterology +7

Transcutaneous immunization using a dissolving microneedle array protects against tetanus, diphtheria, malaria, and influenza

Kazuhiko Matsuo, Sachiko Hirobe, Yayoi Yokota, +9

Journal of Controlled Release

VaccinationMucosal VaccinationCross-protectionVaccine DevelopmentVaccine Target +7