Human uracil–DNA glycosylase deficiency associated with profoundly impaired immunoglobulin class-switch recombination

Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Masamichi Muramatsu, Kazuo Kinoshita, Sidonia Fagarasan et al. · Cell · 2000 · 3.4K citations

Natural Sciences, Genetics, Rna Biology +7

Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)

Patrick Revy, Taro Muto, Yves Lévy et al. · Cell · 2000 · 1.6K citations · Full text

Mendelian Disorder, Autoimmune Disease, Genetic Disorder +8

Specific Expression of Activation-induced Cytidine Deaminase (AID), a Novel Member of the RNA-editing Deaminase Family in Germinal Center B Cells

Masamichi Muramatsu, V.S. Sankaranand, Shrikant Anant et al. · Journal of Biological Chemistry · 1999 · 1.1K citations · Full text

The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

Tsutomu Kawabe, Tetsuji Naka, Kanji Yoshida et al. · Immunity · 1994 · 1.1K citations

Cd40-deficient Mice, Autoimmune Disease, Allergy +10

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

Svend K. Petersen‐Mahrt, Reuben S. Harris, Michael S. Neuberger · Nature · 2002 · 884 citations

E. Coli, Antibody Diversification, Genetics +10