Concepedia

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

Meritxell Huch, Craig Dorrell, Sylvia F. Boj, Johan H. van Es, Vivian Li, Marc van de Wetering, Toshiro Sato, Karien M. Hamer, Nobuo Sasaki, Milton J. Finegold,

Nature · 2013 · 1.6K citations · 28 references

DOI

Concepts

References

28

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

Toshiro Sato, Robert G.J. Vries, Hugo J.G. Snippert et al. · Nature · 2009 · 7.2K citations

, , +14

Identification of stem cells in small intestine and colon by marker gene Lgr5

Nick Barker, Johan H. van Es, Jeroen Kuipers et al. · Nature · 2007 · 5.7K citations

, , +16

Cell fusion is the principal source of bone-marrow-derived hepatocytes

Xin Wang, Holger Willenbring, Yassmine Akkari et al. · Nature · 2003 · 1.6K citations

, , +13

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

Nick Barker, Meritxell Huch, Pekka Kujala et al. · Cell stem cell · 2010 · 1.5K citations · Full text

, , +10

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

Wim de Lau, Nick Barker, Teck Yew Low et al. · Nature · 2011 · 1.3K citations

, , +9