Long-Term Culture of Genome-Stable Bipotent Stem Cells from Adult Human Liver

Meritxell Huch, Helmuth Gehart, Ruben van Boxtel, +20

Cell

Enormous Replication PotentialAdult Stem CellExpanded CellsOrgan DevelopmentCholangiopathies +26

In vitro expansion of single Lgr5+ liver stem cells induced by Wnt-driven regeneration

Meritxell Huch, Craig Dorrell, Sylvia F. Boj, +11

Nature

Regenerative MedicineVitro ExpansionDevelopmental BiologyMedicineWnt-driven Regeneration +6

Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis

Meritxell Huch, Paola Bonfanti, Sylvia F. Boj, +15

The EMBO Journal

Regenerative MedicineDevelopmental BiologyPancreatic CancerMedicineCell Culture +6

Identification of Enteroendocrine Regulators by Real-Time Single-Cell Differentiation Mapping

Helmuth Gehart, Johan H. van Es, Karien M. Hamer, +5

Cell

Signal TransductionMolecular PhysiologyMedicineEnteroendocrine RegulatorsCell Manipulation +4

Coexpression of BMI-1 and EZH2 polycomb-group proteins is associated with cycling cells and degree of malignancy in B-cell non-Hodgkin lymphoma

Folkert J. van Kemenade, Frank M. Raaphorst, Tjasso Blokzijl, +5

Blood

Characterization of Interactions between the Mammalian Polycomb-Group Proteins Enx1/EZH2 and EED Suggests the Existence of Different Mammalian Polycomb-Group Protein Complexes

Richard G. A. B. Sewalt, Johan van der Vlag, Marco J. Gunster, +6

Molecular and Cellular Biology

Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis

Delilah Hendriks, Jos F. Brouwers, Karien M. Hamer, +9

Nature Biotechnology

RING1 Is Associated with the Polycomb Group Protein Complex and Acts as a Transcriptional Repressor

David Satijn, Marco J. Gunster, Johan van der Vlag, +7

Molecular and Cellular Biology

The Polycomb Group Protein EED Interacts with YY1, and Both Proteins Induce Neural Tissue in <i>Xenopus</i>Embryos

David Satijn, Karien M. Hamer, Jan den Blaauwen, +1

Molecular and Cellular Biology

Xenopus EmbryosBrain DevelopmentGeneticsHpc-hph PcgGenomic Mechanism +16

Coexpression of BMI-1 and EZH2 Polycomb Group Genes in Reed-Sternberg Cells of Hodgkin’s Disease

Frank M. Raaphorst, Folkert J. van Kemenade, Tjasso Blokzijl, +5

American Journal Of Pathology

Disease MechanismLymphocyte DevelopmentGeneticsReed-sternberg CellsDisease Gene Identification +5