TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Raja Atreya, Jonas Mudter, Susetta Finotto et al. · Nature Medicine · 2000 · 1.3K citations

Inflammation, Chronic Inflammatory Diseases, Cytokine +11

Role of IL-6 and Its Soluble Receptor in Induction of Chemokines and Leukocyte Recruitment

Maria Romano, Marina Sironi, Carlo Toniatti et al. · Immunity · 1997 · 1.1K citations · Full text

Inflammation, Cytokine, Chemokine Biology +10

Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta

Xiao Yang · The EMBO Journal · 1999 · 900 citations · Full text

Inflammation, Autoimmune Disease, T-regulatory Cell +11

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

Suzanne M. Hurst, Thomas S. Wilkinson, Rachel M. McLoughlin et al. · Immunity · 2001 · 808 citations · Full text

Inflammation, Cytokine, Acute Inflammation +12

A novel inflammation‐related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate

Takuji Tanaka, Hiroyuki Kohno, Rikako Suzuki et al. · Cancer Science · 2003 · 719 citations · Full text