Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF‐β

Interleukin-10-deficient mice develop chronic enterocolitis

Ralf Kühn, Jürgen Löhler, D Rennick et al. · Cell · 1993 · 4.3K citations

Veterinary Medicine, Immunology, Infectious Diseases +14

Direct binding of Smad3 and Smad4 to critical TGFβ‐inducible elements in the promoter of human plasminogen activator inhibitor‐type 1 gene

Sylviane Dennler · The EMBO Journal · 1998 · 1.8K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +9

Ulcerative colitis-like disease in mice with a disrupted interleukin-2 gene

Benjamin Sadlack, Hartmut Merz, Hubert Schorle et al. · Cell · 1993 · 1.7K citations

Veterinary Medicine, Immunology, Pathology +14

The MAD-Related Protein Smad7 Associates with the TGFβ Receptor and Functions as an Antagonist of TGFβ Signaling

Hidetoshi Hayashi, Shirin Abdollah, Yubin Qiu et al. · Cell · 1997 · 1.3K citations · Full text

Life Sciences, Cell Biology, Cell Signaling +7

Transforming growth factor type beta induces monocyte chemotaxis and growth factor production.

Sharon M. Wahl, D A Hunt, Lalage M. Wakefield et al. · Proceedings of the National Academy of Sciences · 1987 · 1.3K citations · Full text

Life Sciences, Cell Biology, Immunology +17