IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

Impaired immune and acute-phase responses in interleukin-6-deficient mice

Manfred Köpf, Heinz Baumann, Giulia Freer et al. · Nature · 1994 · 1.8K citations

Life Sciences, Immunology, Pathology +16

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses.

Jack Gauldie, Gerard Cox, Heinz Baumann et al. · Journal of Clinical Investigation · 1998 · 1.5K citations · Full text

Veterinary Medicine, Immunology, Pathology +17

Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Raja Atreya, Jonas Mudter, Susetta Finotto et al. · Nature Medicine · 2000 · 1.3K citations

Life Sciences, Immunology, Pathology +17

Role of IL-6 and Its Soluble Receptor in Induction of Chemokines and Leukocyte Recruitment

Maria Romano, Marina Sironi, Carlo Toniatti et al. · Immunity · 1997 · 1.1K citations · Full text

Life Sciences, Cell Biology, Immunology +14

Correlations and interactions in the production of interleukin-6 (IL- 6), IL-1, and tumor necrosis factor (TNF) in human blood mononuclear cells: IL-6 suppresses IL-1 and TNF

R. N. Schindler, Stefan Endres, R Ghorbani et al. · Blood · 1990 · 995 citations · Full text

Veterinary Medicine, Cell Biology, Immunology +11