Concepedia

Impaired immune and acute-phase responses in interleukin-6-deficient mice

Manfred Köpf, Heinz Baumann, Giulia Freer, Marina A. Freudenberg, Marinus C. Lamers, Tadamitsu Kishimoto, Rolf M. Zinkernagel, Horst Bluethmann, Georges Köhler

Nature · 1994 · 1.8K citations · 24 references

DOI

Concepts

References

24

Release of reactive nitrogen intermediates and reactive oxygen intermediates from mouse peritoneal macrophages. Comparison of activating cytokines and evidence for independent production.

Aihao Ding, Carl Nathan, Dennis J. Stuehr · The Journal of Immunology · 1988 · 2.8K citations · Full text

, , +17

The biology of interleukin-6

Tadamitsu Kishimoto · Blood · 1989 · 1.9K citations

, , +10

Multiple Defects of Immune Cell Function in Mice with Disrupted Interferon-γ Genes

Dyana K. Dalton, Sharon Pitts-Meek, Satish Keshav et al. · Science · 1993 · 1.7K citations

, , +17

Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

Klaus Pfeffer, T. Matsuyama, Thomas M. Kündig et al. · Cell · 1993 · 1.7K citations

, , +16

Immune Response in Mice that Lack the Interferon-γ Receptor

Sui Huang, Wiljan Hendriks, Alana Althage et al. · Science · 1993 · 1.6K citations · Full text

, , +17