Concepedia

Innate Immune Cell Dysfunction

Innate Immune Cell Dysfunction is a pathophysiological condition characterized by the impaired ability of innate immune cells to appropriately recognize, respond to, and clear pathogens and modulate inflammation, resulting in dysregulated host defense and tissue homeostasis during sepsis.

526

Publications

34.7K

Citations

4.8K

Authors

1.2K

Institutions

Publications per year

2017–2026

256

Parents

Publications

526

Impaired immune and acute-phase responses in interleukin-6-deficient mice

Manfred Köpf, Heinz Baumann, Giulia Freer et al. · Nature · 1994 · 1.8K citations

, , +16

NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X

John C. Pickup, M. Mattock, Gary Chusney et al. · Diabetologia · 1997 · 1.2K citations · Full text

, , +16

Mice lacking neutrophil elastase reveal impaired host defense against gram negative bacterial sepsis

Abderrazzaq Belaaouaj, Ronald McCarthy, Mary Baumann et al. · Nature Medicine · 1998 · 705 citations

, , +14

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma

David A. Braun, Kelly Street, Kelly P. Burke et al. · Cancer Cell · 2021 · 517 citations · Full text

, , +15

Cold-inducible RNA-binding protein (CIRP) triggers inflammatory responses in hemorrhagic shock and sepsis

Xiaoling Qiang, Weng-Lang Yang, Rongqian Wu et al. · Nature Medicine · 2013 · 453 citations · Full text

, , +16

1–5 of 526

Authors

4.8K

  1. PA
    Peter A. Ward

    University of Michigan, United States

    8 publications · 723 citations

    8

    h-index

  2. AA
    Alfred Ayala

    Rhode Island Hospital, United States

    7 publications · 360 citations

    7

    h-index

  3. JV
    J. Vidya Sarma

    University of Michigan, United States

    6 publications · 657 citations

    6

    h-index

  4. FS
    Firas S. Zetoune

    University of Michigan, United States

    6 publications · 538 citations

    6

    h-index

  5. LL
    Lyle L. Moldawer

    University of Florida, United States

    6 publications · 546 citations

    6

    h-index

1–5 of 4.8K

Institutions

1.2K

  1. Inserm

    Paris, France

    19 h-index

    163 publications

    5.8K citations

  2. University of Michigan

    Ann Arbor, United States

    17 h-index

    125 publications

    9.1K citations

  3. Harvard University

    Cambridge, United States

    16 h-index

    86 publications

    12.9K citations

  4. Assistance Publique – Hôpitaux de Paris

    Paris, France

    11 h-index

    60 publications

    2.6K citations

  5. Université Paris Cité

    Paris, France

    10 h-index

    80 publications

    2.7K citations

  6. University College London

    London, United Kingdom

    10 h-index

    44 publications

    4.4K citations

  7. Brown University

    Providence, United States

    10 h-index

    45 publications

    2.2K citations

  8. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    72 publications

    2.1K citations

1–8 of 1.2K

Venues

  1. The Journal of Immunology

    JI · 33 publications · 3.1K citations

    31

    h-index

  2. Frontiers in Immunology

    24 publications · 953 citations

    17

    h-index

  3. International Immunopharmacology

    14 publications · 769 citations

    12

    h-index

  4. Scientific Reports

    12 publications · 634 citations

    12

    h-index

  5. Journal of Leukocyte Biology

    JLB · 12 publications · 831 citations

    12

    h-index

1–5