Alfred Ayala

MyD88-dependent expansion of an immature GR-1+CD11b+ population induces T cell suppression and Th2 polarization in sepsis

Matthew J. Delano, Philip O. Scumpia, Jason S. Weinstein et al. · The Journal of Experimental Medicine · 2007 · 645 citations · Full text

Life Sciences, Immunology, Pathobiology +17

PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

Xin Huang, Fabienne Venet, Yvonne L. Wang et al. · Proceedings of the National Academy of Sciences · 2009 · 506 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

Females in proestrus state maintain splenic immune functions and tolerate sepsis better than males

René Zellweger, Matthias W. Wichmann, Alfred Ayala et al. · Critical Care Medicine · 1997 · 397 citations

Veterinary Medicine, Immunology, Pathobiology +16

Programmed death-1 levels correlate with increased mortality, nosocomial infection and immune dysfunctions in septic shock patients

Caroline Guignant, Alain Lepape, Xin Huang et al. · Critical Care · 2011 · 310 citations · Full text

Veterinary Medicine, Immunology, Pathology +13

Increased circulating regulatory T cells (CD4+CD25+CD127−) contribute to lymphocyte anergy in septic shock patients

Fabienne Venet, Chun‐Shiang Chung, Hakim Kherouf et al. · Intensive Care Medicine · 2008 · 309 citations

Life Sciences, Immunology, Pathobiology +14