Alain Lepape

Global burden of bacterial antimicrobial resistance 1990–2021: a systematic analysis with forecasts to 2050

Mohsen Naghavi, Kevin S Ikuta, Lucien R Swetschinski et al. · The Lancet · 2024 · 2.2K citations · Full text

Global Burden, Antimicrobial Susceptibility, Antimicrobial Stewardship +12

Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock

Guillaume Monneret, Alain Lepape, Nicolas Voirin et al. · Intensive Care Medicine · 2006 · 532 citations

Inflammation, Granulocyte, Low Monocyte +10

PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

Xin Huang, Fabienne Venet, Yvonne L. Wang et al. · Proceedings of the National Academy of Sciences · 2009 · 497 citations · Full text

Innate Immune System, Immunology, Immune Regulation +18

36th International Symposium on Intensive Care and Emergency Medicine

R. M. Bateman, Michael D. Sharpe, Justin E. Jagger et al. · Critical Care · 2016 · 485 citations · Full text

Skin antisepsis with chlorhexidine–alcohol versus povidone iodine–alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial

Olivier Mimoz, Jean‐Christophe Lucet, Thomas Kerforne et al. · The Lancet · 2015 · 317 citations

Antibiotics, Antimicrobial Stewardship, Healthcare-associated Infection +7