Concepedia

Oxidized purine nucleotides, genome instability and neurodegeneration

Ilenia Ventura, Maria Teresa Russo, Gabriele De Luca, Margherita Bignami

Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2010 · 25 citations · 78 references

DOI

Concepts

References

78

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

Shinya Shibutani, Masaru Takeshita, Arthur P. Grollman · Nature · 1991 · 2.2K citations

, , +13

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

Patrizia Mecocci, Usha MacGarvey, M. Flint Beal · Annals of Neurology · 1994 · 1K citations

, , +15

MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

Hisaji Maki, Mutsuo Sekiguchi · Nature · 1992 · 893 citations

, , +8

Oxidative damage and metabolic dysfunction in Huntington's disease: Selective vulnerability of the basal ganglia

Susan Browne, Allen C. Bowling, Usha MacGarvey et al. · Annals of Neurology · 1997 · 872 citations

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