Concepedia

Oxidative Base Modifications

Oxidative Base Modifications is a type of DNA lesion characterized by the chemical alteration of nitrogenous bases through reactive oxygen species, leading to structural and functional impairments in genetic material.

732

Publications

58.9K

Citations

2.4K

Authors

630

Institutions

Publications per year

2017–2026

56

Parents

Publications

732

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

Shinya Shibutani, Masaru Takeshita, Arthur P. Grollman · Nature · 1991 · 2.2K citations

, , +13

DNA damage and mutation in human cells exposed to nitric oxide in vitro.

Tam T. Nguyen, Don Carlos Brunson, Charles L. Crespi et al. · Proceedings of the National Academy of Sciences · 1992 · 980 citations

, , +15

Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA

Steven D. Bruner, Derek P. G. Norman, Gregory L. Verdine · Nature · 2000 · 976 citations

, , +13

Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA

Andrew Collins, Susan J. Duthie, Victoria L. Dobson · Carcinogenesis · 1993 · 821 citations

, , +15

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

Arne Klungland, Ian Rosewell, Stephan Hollenbach et al. · Proceedings of the National Academy of Sciences · 1999 · 798 citations

, , +17

1–5 of 732

Authors

2.4K

  1. MD
    Miral Dizdaroğlu

    National Institute of Standards and Technology, United States

    28 publications · 4K citations

    28

    h-index

  2. JC
    Jean Cadet

    CEA Grenoble, France

    26 publications · 1.8K citations

    22

    h-index

  3. BE
    Bernd Epe

    Johannes Gutenberg University Mainz, Germany

    23 publications · 2.1K citations

    20

    h-index

  4. BH
    Barry Halliwell

    King's College London, United Kingdom

    20 publications · 3.1K citations

    20

    h-index

  5. CJ
    Cynthia J. Burrows

    University of Utah, United States

    20 publications · 1.4K citations

    17

    h-index

1–5 of 2.4K

Institutions

630

  1. National Institute of Standards and Technology

    Gaithersburg, United States

    37 h-index

    103 publications

    15.8K citations

  2. Commissariat à l'Énergie Atomique et aux Énergies Alternatives

    Paris, France

    33 h-index

    105 publications

    8.8K citations

  3. CEA Grenoble

    Grenoble, France

    26 h-index

    80 publications

    6.5K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    25 h-index

    94 publications

    5.7K citations

  5. University of Utah

    Salt Lake City, United States

    19 h-index

    81 publications

    6.3K citations

  6. Johannes Gutenberg University Mainz

    Mainz, Germany

    19 h-index

    56 publications

    10.6K citations

  7. The University of Texas Medical Branch at Galveston

    Galveston, United States

    18 h-index

    89 publications

    7.2K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    17 h-index

    67 publications

    10.2K citations

1–8 of 630

Venues

  1. Nucleic Acids Research

    67 publications · 6.5K citations

    46

    h-index

  2. Chemical Research in Toxicology

    54 publications · 3.3K citations

    34

    h-index

  3. Biochemistry

    49 publications · 2.8K citations

    33

    h-index

  4. Journal of Biological Chemistry

    JBC · 32 publications · 3.8K citations

    31

    h-index

  5. Carcinogenesis

    35 publications · 4K citations

    28

    h-index

1–5