Activities and relative affinities of divalent metals in unmodified and phosphorothioate-substituted hammerhead ribozymes

Absolute electronegativity and hardness: application to inorganic chemistry

Ralph G. Pearson · Inorganic Chemistry · 1988 · 3.3K citations

Materials Science, Inorganic Chemistry, Chemical Engineering +15

Oligoribonucleotide synthesis using T7 RNA polymerase and synthetic DNA templates

John F. Milligan, Duncan R. Groebe, Gary W. Witherell et al. · Nucleic Acids Research · 1987 · 2.2K citations · Full text

Three-dimensional structure of a hammerhead ribozyme

Heinz W. Pley, Kevin Flaherty, David McKay · Nature · 1994 · 952 citations

Structural Morphology, Protein Folding, Protein X-ray Crystallography +7

The crystal structure of an AII-RNAhammerhead ribozyme: A proposed mechanism for RNA catalytic cleavage

W. G. Scott, J.T. Finch, Aaron Klug · Cell · 1995 · 684 citations · Full text

Crystal Structure, Biochemistry, Natural Sciences +7

Self-cleavage of plus and minus RNAs of a virusoid and a structural model for the active sites

Anthony Forster, Robert H. Symons · Cell · 1987 · 665 citations

Virus Structure, Viral Replication, Systems Biology +12