Concepedia

Ribozyme Engineering

Ribozyme Engineering is a methodological framework within RNA Engineering that involves the design and optimization of catalytic RNA molecules to perform specific biochemical reactions through targeted modifications of their sequence and structural motifs.

770

Publications

43.2K

Citations

2.4K

Authors

619

Institutions

Publications per year

2017–2026

67

Parents

Publications

770

Three-dimensional structure of a hammerhead ribozyme

Heinz W. Pley, Kevin Flaherty, David McKay · Nature · 1994 · 957 citations

, , +14

Control of gene expression by a natural metabolite-responsive ribozyme

Wade C. Winkler, Ali Nahvi, Adam Roth et al. · Nature · 2004 · 954 citations

, , +12

Self‐processing of ribozyme‐flanked RNAs into guide RNAs <i>in vitro</i> and <i>in vivo</i> for CRISPR‐mediated genome editing

Yangbin Gao, Yunde Zhao · Journal of Integrative Plant Biology · 2013 · 578 citations · Full text

, , +15

Structurally Complex and Highly Active RNA Ligases Derived from Random RNA Sequences

Eric H. Ekland, Jack W. Szostak, David P. Bartel · Science · 1995 · 423 citations

, , +13

Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa

Alfred S. Lewin, Kimberly A. Drenser, William W. Hauswirth et al. · Nature Medicine · 1998 · 406 citations

, , +17

1–5 of 770

Authors

2.4K

  1. JJ
    John J. Rossi

    City of Hope, United States

    19 publications · 849 citations

    15

    h-index

  2. RR
    Ronald R. Breaker

    Yale University, United States

    15 publications · 2.4K citations

    14

    h-index

  3. WG
    Wen G. Jiang

    Cardiff University, United Kingdom

    15 publications · 557 citations

    14

    h-index

  4. HS
    Hiroaki Suga

    The University of Tokyo, Japan

    14 publications · 781 citations

    13

    h-index

  5. KT
    Kazunari Taira

    National Institute of Advanced Industrial Science and Technology, Japan

    16 publications · 606 citations

    13

    h-index

1–5 of 2.4K

Institutions

619

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    22 h-index

    68 publications

    5.3K citations

  2. Stanford University

    Stanford, United States

    19 h-index

    80 publications

    7.1K citations

  3. Yale University

    New Haven, United States

    19 h-index

    64 publications

    10.4K citations

  4. The University of Tokyo

    Tokyo, Japan

    17 h-index

    63 publications

    2.9K citations

  5. University of California San Diego

    San Diego, United States

    17 h-index

    71 publications

    8K citations

  6. University of Colorado Boulder

    Boulder, United States

    16 h-index

    27 publications

    2.6K citations

  7. University of California, Berkeley

    Berkeley, United States

    16 h-index

    94 publications

    3.2K citations

  8. Scripps Research Institute

    San Diego, United States

    16 h-index

    40 publications

    3K citations

1–8 of 619

Venues

  1. Nucleic Acids Research

    56 publications · 3K citations

    35

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 34 publications · 3.6K citations

    30

    h-index

  3. PubMed

    Repository · 45 publications · 2.4K citations

    27

    h-index

  4. Journal of Molecular Biology

    JMB · 28 publications · 1.6K citations

    23

    h-index

  5. RNA

    27 publications · 1.3K citations

    21

    h-index

1–5