Alfred S. Lewin

Dysregulated autophagy in the RPE is associated with increased susceptibility to oxidative stress and AMD

Sayak K. Mitter, Chunjuan Song, Xiaoping Qi et al. · Autophagy · 2014 · 431 citations · Full text

Mitophagy, Autophagic Dysregulation, Lipid Peroxidation +18

Ribozyme rescue of photoreceptor cells in a transgenic rat model of autosomal dominant retinitis pigmentosa

Alfred S. Lewin, Kimberly A. Drenser, William W. Hauswirth et al. · Nature Medicine · 1998 · 406 citations

Photoreceptor Cell, Retina, Photoreceptor Cells +7

High-efficiency Transduction of the Mouse Retina by Tyrosine-mutant AAV Serotype Vectors

Hilda Petrs‐Silva, Astra Dinculescu, Qiuhong Li et al. · Molecular Therapy · 2008 · 389 citations · Full text

Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78

Marina S. Gorbatyuk, Tessa Knox, Matthew M. LaVail et al. · Proceedings of the National Academy of Sciences · 2010 · 285 citations · Full text

Intrastriatal rAAV-mediated delivery of anti-huntingtin shRNAs induces partial reversal of disease progression in R6/1 Huntington's disease transgenic mice

Edgardo Rodríguez-Lebrón, Eileen M. Denovan‐Wright, Kevin Nash et al. · Molecular Therapy · 2005 · 275 citations · Full text