Concepedia

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

Rozalyn M. Anderson, Kevin J. Bitterman, Jason G. Wood, Oliver Medvedik, David Sinclair

Nature · 2003 · 735 citations · 28 references

DOI

Concepts

References

28

Genomic Expression Programs in the Response of Yeast Cells to Environmental Changes

Audrey P. Gasch, Paul T. Spellman, Camilla M. Kao et al. · Molecular Biology of the Cell · 2000 · 4.9K citations · Full text

, , +17

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

Shin‐ichiro Imai, Christopher M. Armstrong, Matt Kaeberlein et al. · Nature · 2000 · 3.5K citations

, , +16

hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Homayoun Vaziri, Scott Dessain, Elinor Ng Eaton et al. · Cell · 2001 · 2.6K citations · Full text

, , +8

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

Matt Kaeberlein, Mitch McVey, Leonard Guarente · Genes & Development · 1999 · 2.3K citations · Full text

, , +9

Negative Control of p53 by Sir2α Promotes Cell Survival under Stress

Jianyuan Luo, Anatoly Nikolaev, Shin‐ichiro Imai et al. · Cell · 2001 · 2.1K citations · Full text

, , +14