Concepedia

Nicotinamide Deficiency

Nicotinamide Deficiency is a biochemical disorder characterized by insufficient levels of nicotinamide, a form of vitamin B3, leading to impaired cellular metabolism and manifestations of pellagra, distinguished from other micronutrient deficiencies by its specific role in NAD-dependent redox reactions and DNA repair processes.

133

Publications

6K

Citations

582

Authors

264

Institutions

Publications per year

2017–2026

29

Variants

Niacin DeficiencyVitamin B3 Deficiency

Parents

Publications

133

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

Rozalyn M. Anderson, Kevin J. Bitterman, Jason G. Wood et al. · Nature · 2003 · 735 citations

, , +16

NAD <sup>+</sup> supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

Yujun Hou, Sofie Lautrup, Stephanie A. Cordonnier et al. · Proceedings of the National Academy of Sciences · 2018 · 465 citations · Full text

, , +17

Mechanism of deoxyadenosine and 2-chlorodeoxyadenosine toxicity to nondividing human lymphocytes.

S Seto, C J Carrera, Masaru Kubota et al. · Journal of Clinical Investigation · 1985 · 388 citations · Full text

, , +13

Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast

Matt Kaeberlein, Di Hu, Emily O. Kerr et al. · PLoS Genetics · 2005 · 193 citations · Full text

, , +17

Nicotinamide Ameliorates Disease Phenotypes in a Human iPSC Model of Age-Related Macular Degeneration

Janmeet S. Saini, Barbara Corneo, Justine D. Miller et al. · Cell stem cell · 2017 · 182 citations · Full text

, , +12

1–5 of 133

Authors

582

  1. CE
    C.A. Elvehjem

    University of Wisconsin–Madison, United States

    4 publications · 89 citations

    4

    h-index

  2. AE
    A. E. Axelrod

    University of Pittsburgh, United States

    3 publications · 79 citations

    3

    h-index

  3. AW
    Adrian Williams

    University of Birmingham, United Kingdom

    3 publications · 90 citations

    3

    h-index

  4. TD
    Tom D. Spies

    Northwestern University, United States

    3 publications · 67 citations

    3

    h-index

  5. SB
    Sylvia B. Zak

    Novartis (Switzerland), Switzerland

    3 publications · 44 citations

    3

    h-index

1–5 of 582

Institutions

264

  1. University of Wisconsin–Madison

    Madison, United States

    6 h-index

    6 publications

    176 citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    3 publications

    152 citations

  3. University College London

    London, United Kingdom

    3 h-index

    3 publications

    113 citations

  4. Harvard University

    Cambridge, United States

    3 h-index

    3 publications

    861 citations

  5. Middlesex Hospital

    Middletown, United States

    2 h-index

    2 publications

    70 citations

  6. Chinese Academy of Medical Sciences & Peking Union Medical College

    Beijing, China

    2 h-index

    2 publications

    86 citations

  7. Newcastle University

    Newcastle upon Tyne, United Kingdom

    2 h-index

    2 publications

    32 citations

  8. Université d'Angers

    Angers, France

    2 h-index

    2 publications

    136 citations

1–8 of 264

Venues

  1. PubMed

    Repository · 9 publications · 197 citations

    9

    h-index

  2. Journal of Biological Chemistry

    JBC · 5 publications · 172 citations

    5

    h-index

  3. Nature

    4 publications · 803 citations

    4

    h-index

  4. Science

    4 publications · 140 citations

    4

    h-index

  5. Medical Hypotheses

    3 publications · 74 citations

    3

    h-index

1–5