The synthesis of peptidomimetic combinatorial libraries through successive amide alkylations

<b>Solid Phase Peptide Synthesis. I. The Synthesis of a Tetrapeptide</b>

R. B. Merrifield · Journal of the American Chemical Society · 1963 · 7.6K citations

Natural Sciences, Biochemistry, Chemistry +6

Color test for detection of free terminal amino groups in the solid-phase synthesis of peptides

E. T. Kaiser, Robert L. Colescott, C.D. Bossinger et al. · Analytical Biochemistry · 1970 · 3.5K citations

Natural Sciences, Biochemistry, Protein Biochemistry +10

A new type of synthetic peptide library for identifying ligand-binding activity

Kit S. Lam, Sydney E. Salmon, Evan M. Hersh et al. · Nature · 1991 · 1.8K citations

Pharmacy, Biochemistry, Medicinal Chemistry +16

Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery

Richard A. Houghten, Clemencia Pinilla, Sylvie E. Blondelle et al. · Nature · 1991 · 1.3K citations

Pharmacy, Biotechnology, Medicinal Chemistry +16

General method for rapid synthesis of multicomponent peptide mixtures

Árpád Furka, Ferenc Sebestyén, MAMO ASGEDOM et al. · International journal of peptide & protein research · 1991 · 1.2K citations

Pharmacy, Biochemistry, Chemistry +10