Towards consensus practices to qualify safety biomarkers for use in early drug development

Comparing the Areas under Two or More Correlated Receiver Operating Characteristic Curves: A Nonparametric Approach

Elizabeth R. DeLong, David M. DeLong, Daniel L. Clarke‐Pearson · Biometrics · 1988 · 22.3K citations

Natural Sciences, Biostatistics, Diagnostic Assessment +16

The environment and disease: association or causation?

Austin Bradford Hill · Journal of the Royal Society of Medicine · 2015 · 7.3K citations · Full text

Public Health, Environmental Sciences, Environmental Health +9

Myocardial infarction redefined—a consensus document of The Joint European Society of Cardiology/American College of Cardiology committee for the redefinition of myocardial infarction

Elliott M. Antman, Jean‐Pierre Bassand, Werner Klein et al. · Journal of the American College of Cardiology · 2000 · 4.8K citations

Medicine, Cardiology, Internal Medicine +16

Fit-for-Purpose Method Development and Validation for Successful Biomarker Measurement

Jean W. Lee, Viswanath Devanarayan, Yu Chen Barrett et al. · Pharmaceutical Research · 2006 · 759 citations

Pharmacy, Biostatistics, Method Validation +11

Kidney injury molecule-1: a tissue and urinary biomarker for nephrotoxicant-induced renal injury

Takaharu Ichimura, Cheng Chieh Hung, Soon Ae Yang et al. · American Journal of Physiology-Renal Physiology · 2004 · 673 citations

Medicine, Pathology, Toxicology +16