Graham R. Betton

Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium

Frank Dieterle, Frank D. Sistare, Federico Goodsaid et al. · Nature Biotechnology · 2010 · 406 citations

Medicine, Nephrology, Precision Medicine +13

Proliferative and Nonproliferative Lesions of the Rat and Mouse Urinary System

Kendall S. Frazier, John Curtis Seely, Gordon C. Hard et al. · Toxicologic Pathology · 2012 · 295 citations

Veterinary Medicine, Pathology, Toxicology +14

Towards consensus practices to qualify safety biomarkers for use in early drug development

Frank D. Sistare, Frank Dieterle, Sean P. Troth et al. · Nature Biotechnology · 2010 · 121 citations

Pharmacy, Pharmacology, Regulatory Pharmacy +16

Biological Qualification of Biomarkers of Chemical-Induced Renal Toxicity in Two Strains of Male Rat

Ernie Harpur, Daniela Ennulat, David Hoffman et al. · Toxicological Sciences · 2011 · 121 citations · Full text

Medicine, Pathology, Toxicology +17

Gastric ECL-Cell Hyperplasia and Carcinoids in Rodents Following Chronic Administration of H ₂ -Antagonists SK&F 93479 and Oxmetidine and Omeprazole

Graham R. Betton, Charles S. Dormer, T.C.E. Wells et al. · Toxicologic Pathology · 1988 · 115 citations · Full text

Medicine, Oncology, Pharmacology +16