Concepedia

Pirh2, a p53-Induced Ubiquitin-Protein Ligase, Promotes p53 Degradation

Roger Leng, Yunping Lin, Weili Ma, Hong Wu, Bénédicte Lemmers, Stephen W. Chung, John M. Parant, Guillermina Lozano, Razqallah Hakem, Samuel Benchimol

Cell · 2003 · 720 citations · 36 references

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36

Surfing the p53 network

Bert Vogelstein, David P. Lane, Arnold J. Levine · Nature · 2000 · 6.6K citations

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Mdm2 promotes the rapid degradation of p53

Ygal Haupt, Ruth Maya, Anat Kazaz et al. · Nature · 1997 · 4.5K citations

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Regulation of p53 stability by Mdm2

Michael H.G. Kubbutat, Stephen N. Jones, Karen H. Vousden · Nature · 1997 · 3.3K citations

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The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

Jamil Momand, Gerard P. Zambetti, David C. Olson et al. · Cell · 1992 · 3.1K citations

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hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase

Homayoun Vaziri, Scott Dessain, Elinor Ng Eaton et al. · Cell · 2001 · 2.6K citations · Full text

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