John M. Parant

The Tol2kit: A multisite gateway‐based construction kit for <i>Tol2</i> transposon transgenesis constructs

Kristen M. Kwan, E. Fujimoto, Clemens Grabher et al. · Developmental Dynamics · 2007 · 1.9K citations

Gain of Function of a p53 Hot Spot Mutation in a Mouse Model of Li-Fraumeni Syndrome

Gene A. Lang, Tomoo Iwakuma, Young‐Ah Suh et al. · Cell · 2004 · 1.1K citations · Full text

Knockout Mouse, Li-fraumeni Syndrome, Genome Instability +7

Pirh2, a p53-Induced Ubiquitin-Protein Ligase, Promotes p53 Degradation

Roger Leng, Yunping Lin, Weili Ma et al. · Cell · 2003 · 714 citations · Full text

Molecular Regulation, Promotes P53 Degradation, Cell Death +5

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53

John M. Parant, Arturo Chávez‐Reyes, Natalie A Little et al. · Nature Genetics · 2001 · 512 citations

Knockout Mouse, Tumor Biology, Genome Instability +10

Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice

Geng Liu, John M. Parant, Gene A. Lang et al. · Nature Genetics · 2003 · 319 citations · Full text

Chromatin, Tumor Biology, Genome Instability +12