Concepedia

Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer

S A Ridge, J Sludden, Xiaoxiong Wei, Andrea Sapone, Oliver E. Brown, Sally Hardy, PA Canney, Pedro M. Fernández‐Salguero, J Cassidy, H. L. McLeod

British Journal of Cancer · 1998 · 93 citations · 11 references

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References

11

Clinical pharmacokinetics of 5-fluorouracil and its metabolites in plasma, urine, and bile.

Glen D. Heggie, Jean‐Pierre Sommadossi, David S. Cross et al. · PubMed · 1987 · 731 citations

, , +17

Familial deficiency of dihydropyrimidine dehydrogenase. Biochemical basis for familial pyrimidinemia and severe 5-fluorouracil-induced toxicity.

Robert B. Diasio, T L Beavers, John T. Carpenter · Journal of Clinical Investigation · 1988 · 500 citations · Full text

, , +14

Population study of dihydropyrimidine dehydrogenase in cancer patients.

M C Etienne, J.-L. Lagrange, O. Dassonville et al. · Journal of Clinical Oncology · 1994 · 432 citations

, , +15

Dihydropyrimidine dehydrogenase activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients, and clinical implication in 5-fluorouracil chemotherapy.

Zhihong Lu, Ruiwen Zhang, Robert B. Diasio · PubMed · 1993 · 374 citations

, , +14

Molecular basis of the human dihydropyrimidine dehydrogenase deficiency and 5-fluorouracil toxicity.

Xiaoxiong Wei, Howard L. McLeod, J McMurrough et al. · Journal of Clinical Investigation · 1996 · 360 citations · Full text

, , +17