A Phase I clinical study of cisplatin-incorporated polymeric micelles (NC-6004) in patients with solid tumours

Ruth Plummer, Richard H. Wilson, Hilary Calvert, +10

British Journal of Cancer

The frequency and distribution of thiopurine methyltransferase alleles in Caucasian and Asian populations

Elaina Collie–Duguid, Pritchard, Powrie, +4

Pharmacogenetics

Influence of pharmacogenetics on response and toxicity in breast cancer patients treated with doxorubicin and cyclophosphamide

Johanne Bray, J Sludden, Martin J. Griffin, +4

British Journal of Cancer

Characterization of dihydropyrimidine dehydrogenase in human colorectal tumours

H. L. McLeod, J Sludden, G I Murray, +5

British Journal of Cancer

Tumor BiologyBiochemistryOncogenic AgentMedicineColorectal Cancer +3

Dihydropyrimidine dehydrogenase pharmacogenetics in patients with colorectal cancer

S A Ridge, J Sludden, Xiaoxiong Wei, +7

British Journal of Cancer

OncologyMedicineColorectal CancerPharmacologyCancer Research

Ethnic differences in catechol O-methyltransferase pharmacogenetics: frequency of the codon 108/158 low activity allele is lower in Kenyan than Caucasian or South-west Asian individuals.

H. L. McLeod, Ann-Christine Syvänen, Jessie Githanga, +5

PubMed

Comt ActivityErythrocyte Comt ActivityGeneticsGenetic EpidemiologyHuman Polymorphism +14

Autoregulation of 5-fluorouracil metabolism

Howard L. McLeod, J Sludden, Sarah Hardy, +3

European Journal of Cancer

BiochemistryMedicineNatural SciencesCatabolismAutophagy +6

Pharmacogenetics of adjuvant breast cancer treatment with cyclophosphamide, epirubicin and 5-fluorouracil

David Jamieson, Jo Lee, Nicola Cresti, +4

Cancer Chemotherapy and Pharmacology

Breast OncologyOncologyMedicineBreast CancerPharmacotherapy +4

Phase I and pharmacokinetic study of DACA (XR5000): a novel inhibitor of topoisomerase I and II

Chris Twelves, C. Gardner, A. Flavin, +10

British Journal of Cancer

The Encapsulation of Bleomycin Within Chitosan Based Polymeric Vesicles Does Not Alter its Biodistribution

J Sludden, Ijeoma F. Uchegbu, Andreas G. Schätzlein

Journal of Pharmacy and Pharmacology

Palmitoyl Glycol ChitosanNanomedicineSmaller VesiclesLipid PreparationEngineering +13