Recruitment of TRRAP required for oncogenic transformation by E1A

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Hartmut Land, Luis F. Parada, Robert A. Weinberg · Nature · 1983 · 2.9K citations

Developmental Biology, Tumor Heterogeneity, Least Two +9

Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

Jay P. Morgenstern, Hartmut Land · Nucleic Acids Research · 1990 · 2.1K citations · Full text

Viral Replication, Engineering, Medicine +15

Involvement of the TIP60 Histone Acetylase Complex in DNA Repair and Apoptosis

Tsuyoshi Ikura, Vasily Ogryzko, Mikhaïl Grigoriev et al. · Cell · 2000 · 1K citations · Full text

Chromatin, Genome Instability, Chromatin Remodeling +7

Cellular targets for transformation by the adenovirus E1A proteins

Peter Whyte, Nicola M. Williamson, Ed Harlow · Cell · 1989 · 754 citations

Adenovirus E1a Proteins, Signal Transduction, Molecular Biology +5

The Novel ATM-Related Protein TRRAP Is an Essential Cofactor for the c-Myc and E2F Oncoproteins

Steven B. McMahon, Heather A. Van Buskirk, Kerri A Dugan et al. · Cell · 1998 · 692 citations · Full text

E2f Oncoproteins, Protein Function, Signal Transduction +10