Human Origin Recognition Complex Large Subunit Is Degraded by Ubiquitin-Mediated Proteolysis after Initiation of DNA Replication

Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells

Sayda M. Elbashir, Jens Harborth, Winfried Lendeckel et al. · Nature · 2001 · 9.3K citations

Natural Sciences, Rna Splicing, Rna Biology +9

AAA⁺: A Class of Chaperone-Like ATPases Associated with the Assembly, Operation, and Disassembly of Protein Complexes

Andrew F. Neuwald, L. Aravind, John L. Spouge et al. · Genome Research · 1999 · 1.8K citations · Full text

SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27

Andrea C. Carrano, Esther Eytan, Avram Hershko et al. · Nature Cell Biology · 1999 · 1.5K citations

Ubiquitin-mediated Degradation, Signal Transduction, Cell Regulation +9

Ubiquitin-dependent c-Jun degradation in vivo is mediated by the δ domain

Mathias Treier, Lena Staszewski, Dirk Bohmann · Cell · 1994 · 927 citations

Signal Transduction, Cell Regulation, Molecular Regulation +10

Chromatin Association of Human Origin Recognition Complex, Cdc6, and Minichromosome Maintenance Proteins during the Cell Cycle: Assembly of Prereplication Complexes in Late Mitosis

Juan Méndez, Bruce Stillman · Molecular and Cellular Biology · 2000 · 927 citations · Full text