1,2-disubstituted indole, azaindole and benzimidazole derivatives possessing amine moiety: a novel series of thrombin inhibitors

Dibasic Benzo[<i>b</i>]thiophene Derivatives as a Novel Class of Active Site-Directed Thrombin Inhibitors. 1. Determination of the Serine Protease Selectivity, Structure−Activity Relationships, and Binding Orientation

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Pharmaceutical Science, Altmetric Attention Score, Pharmacotherapy +19

Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 4. SAR studies on the conformationally restricted C3-side chain of hydroxybenzo[b]thiophenes

Kumiko Takeuchi, Todd J. Kohn, Daniel J. Sall et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 35 citations

Medicinal Chemistry, Derivative (Chemistry), Thrombin Inhibitors +10

Diamino Benzo[<i>b</i>]thiophene Derivatives as a Novel Class of Active Site Directed Thrombin Inhibitors. 5. Potency, Efficacy, and Pharmacokinetic Properties of Modified C-3 Side Chain Derivatives

Daniel J. Sall, Dianna L. Bailey, Jolie Bastian et al. · Journal of Medicinal Chemistry · 2000 · 30 citations

Pharmaceutical Science, Pharmacotherapy, Pharmaceutical Chemistry +21

Dibasic benzo[b]thiophene derivatives as a novel class of active site directed thrombin inhibitors: 2: sidechain optimization and demonstration of in vivo efficacy

Minsheng Zhang, Dianna L. Bailey, Jolie Bastian et al. · Bioorganic & Medicinal Chemistry Letters · 1999 · 13 citations · Full text

Thrombosis, Medicinal Chemistry, Sidechain Optimization +12