Concepedia

Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors

Toshihiko Doi, Haruyasu Murakami, A. Ohtsu, Nozomu Fuse, Takayuki Yoshino, Nobuyuki Yamamoto, Narikazu Boku, Yusuke Onozawa, C-P. Hsu, Kevin Gorski,

Cancer Chemotherapy and Pharmacology · 2010 · 49 citations · 24 references

DOI

Concepts

References

24

Identification and characterization of a new member of the TNF family that induces apoptosis

Steven R. Wiley, Ken Schooley, Pamela J. Smolak et al. · Immunity · 1995 · 2.9K citations · Full text

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Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Henning Walczak, Robert E. Miller, K. Ariail et al. · Nature Medicine · 1999 · 2.5K citations

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Safety and antitumor activity of recombinant soluble Apo2 ligand

Avi Ashkenazi, Roger Pai, Sharon Fong et al. · Journal of Clinical Investigation · 1999 · 2.2K citations · Full text

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Induction of Apoptosis by Apo-2 Ligand, a New Member of the Tumor Necrosis Factor Cytokine Family

Robert Pitti, Scot A. Marsters, Siegfried Ruppert et al. · Journal of Biological Chemistry · 1996 · 1.8K citations · Full text

Control of TRAIL-Induced Apoptosis by a Family of Signaling and Decoy Receptors

James P. Sheridan, Scot A. Marsters, Robert Pitti et al. · Science · 1997 · 1.7K citations

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