The E6AP E3 ubiquitin ligase regulates the cellular response to oxidative stress

Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5K citations · Full text

Developmental Biology, Oncogenic Agent, Cellular Senescence +6

A System for Stable Expression of Short Interfering RNAs in Mammalian Cells

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Functional Genomics, Psuper Vector, Short Interfering Rnas +15

The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53

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Human Papillomavirus Vaccines, Medicine, Pathology +10

Stable suppression of tumorigenicity by virus-mediated RNA interference

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Stable Suppression, Rna Biology, Small Rna +4

Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

Simona Parrinello, Enrique Samper, Ana Krtolica et al. · Nature Cell Biology · 2003 · 1.1K citations · Full text

Lifespan Extension, Fibrosis, Aging +12