mRNA acetylated at 2'‐OH‐groups of ribose residues is functionally active in the cell‐free translation system from wheat embryos

Abstract

Modification (acetylation) of 2'-OH groups of mRNA ribose residues does not result in a loss of their template activity in a cell-free translation system from wheat embryos and in some cases activates inactive mRNAs. Modification of 70-75% of 2'-OH groups makes mRNA stable to the effect of pancreatic ribonuclease.