Concepedia

Translational Activation

Translational Activation is a regulatory mechanism within the broader category of translational control that specifically enhances the initiation or efficiency of protein synthesis by promoting ribosome recruitment to specific mRNAs under defined cellular conditions.

916

Publications

79.7K

Citations

4.1K

Authors

1.1K

Institutions

Publications per year

2017–2026

180

Parents

Publications

916

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.9K citations

, , +14

Switching from Repression to Activation: MicroRNAs Can Up-Regulate Translation

Shobha Vasudevan, Yingchun Tong, Joan A. Steitz · Science · 2007 · 2.8K citations

, , +17

A unifying model for mTORC1-mediated regulation of mRNA translation

Carson C. Thoreen, Lynne Chantranupong, Heather R. Keys et al. · Nature · 2012 · 1.5K citations · Full text

, , +16

A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the sam mRNA

Patrick Descombes, Ueli Schibler · Cell · 1991 · 1K citations

, , +15

Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation

B. Nave, D. Margriet Ouwens, Dominic J. Withers et al. · Biochemical Journal · 1999 · 923 citations · Full text

, , +17

1–5 of 916

Authors

4.1K

  1. AG
    Alan G. Hinnebusch

    Eunice Kennedy Shriver National Institute of Child Health and Human Development, United States

    22 publications · 2K citations

    19

    h-index

  2. NS
    Nahum Sonenberg

    McGill University, Canada

    14 publications · 3K citations

    14

    h-index

  3. RC
    Ronald C. Wek

    Indiana University – Purdue University Indianapolis, United States

    11 publications · 775 citations

    11

    h-index

  4. TD
    Thomas D. Fox

    Cornell University, United States

    7 publications · 496 citations

    7

    h-index

  5. SS
    Sidney Strickland

    Rockefeller University, United States

    7 publications · 888 citations

    7

    h-index

1–5 of 4.1K

Institutions

1.1K

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    27 h-index

    80 publications

    19.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    26 h-index

    188 publications

    15.8K citations

  3. Inserm

    Paris, France

    24 h-index

    182 publications

    12.4K citations

  4. Eunice Kennedy Shriver National Institute of Child Health and Human Development

    Bethesda, United States

    22 h-index

    86 publications

    9.2K citations

  5. McGill University

    Montreal, Canada

    21 h-index

    91 publications

    13.2K citations

  6. National Institutes of Health

    Bethesda, United States

    21 h-index

    74 publications

    4.7K citations

  7. University of Washington

    Seattle, United States

    19 h-index

    67 publications

    5.4K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    17 h-index

    56 publications

    11.2K citations

1–8 of 1.1K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 74 publications · 9K citations

    54

    h-index

  2. Journal of Biological Chemistry

    JBC · 72 publications · 6.4K citations

    46

    h-index

  3. Molecular and Cellular Biology

    MCB · 44 publications · 5K citations

    34

    h-index

  4. Nucleic Acids Research

    56 publications · 3.7K citations

    34

    h-index

  5. Genes & Development

    22 publications · 4.1K citations

    22

    h-index

1–5