Concepedia

Studies on the chemistry of rapamycin: Novel transformations under Lewis-acid catalysis

Juan I. Luengo, Arda L. Konialian, Dennis A. Holt

Tetrahedron Letters · 1993 · 38 citations · 22 references

DOI

Concepts

References

22

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity

J. Liu, Mark W. Albers, Thomas J. Wandless et al. · Biochemistry · 1992 · 561 citations

, , +17

Structure of FK506, a novel immunosuppressant isolated from Streptomyces

Hirokazu Tanaka, Akio Kuroda, Hiroshi Marusawa et al. · Journal of the American Chemical Society · 1987 · 514 citations

, , +8

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin.

Francis J. Dumont, Mary Jo Staruch, Sam L. Koprak et al. · The Journal of Experimental Medicine · 1992 · 253 citations · Full text

, , +17

Natural Products as Probes of Cellular Function: Studies of Immunophilins

Michael K. Rosen, Stuart L. Schreiber · Angewandte Chemie International Edition in English · 1992 · 147 citations

, , +15

On the chemistry and high field nuclear magnetic resonance spectroscopy of rapamycin

John A. Findlay, Lajos Radics · Canadian Journal of Chemistry · 1980 · 119 citations · Full text

, , +3