Concepedia

Francis J. Dumont

FJ

70

Publications

4.9K

Citations

28

H-Index

1972

Active since

Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)(Current)

Inserm

Francis J. Dumont is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, immunology, and cell biology.

Top concepts

Publications per year

1972–2010

70

Publications

70

Isolation of a Protein Target of the FKBP12-Rapamycin Complex in Mammalian Cells

Candace J. Sabers, Mary M. Martin, Gregory J. Brunn et al. · Journal of Biological Chemistry · 1995 · 872 citations · Full text

The immunosuppressant FK506 selectively inhibits expression of early T cell activation genes.

Michael J. Tocci, D A Matkovich, Kathy Collier et al. · The Journal of Immunology · 1989 · 669 citations

Distinct mechanisms of suppression of murine T cell activation by the related macrolides FK-506 and rapamycin.

Francis J. Dumont, Mary Jo Staruch, Sam L. Koprak et al. · The Journal of Immunology · 1990 · 607 citations

The immunosuppressive macrolides FK-506 and rapamycin act as reciprocal antagonists in murine T cells.

Francis J. Dumont, Michael Melino, Mary Jo Staruch et al. · The Journal of Immunology · 1990 · 355 citations · Full text

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin.

Francis J. Dumont, Mary Jo Staruch, Sam L. Koprak et al. · The Journal of Experimental Medicine · 1992 · 253 citations · Full text

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