FADD/MORT1 and Caspase-8 Are Recruited to TRAIL Receptors 1 and 2 and Are Essential for Apoptosis Mediated by TRAIL Receptor 2

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

Ildo Nicoletti, Graziella Migliorati, Maria Cristina Pagliacci et al. · Journal of Immunological Methods · 1991 · 4.6K citations

Life Sciences, Cell Biology, Molecular Biology +7

FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex

Marta Muzio, Arul M. Chinnaiyan, Frank Kischkel et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Identification and characterization of a new member of the TNF family that induces apoptosis

Steven R. Wiley, Ken Schooley, Pamela J. Smolak et al. · Immunity · 1995 · 2.9K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14

Tumoricidal activity of tumor necrosis factor–related apoptosis–inducing ligand in vivo

Henning Walczak, Robert E. Miller, K. Ariail et al. · Nature Medicine · 1999 · 2.5K citations

Life Sciences, Oncology, Pharmacology +12

FADD, a novel death domain-containing protein, interacts with the death domain of fas and initiates apoptosis

Arul M. Chinnaiyan, Karen O’Rourke, Muneesh Tewari et al. · Cell · 1995 · 2.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +14