Concepedia

Aire regulates negative selection of organ-specific T cells

Adrian Liston, Sylvie Lesage, Judith Wilson, Leena Peltonen, Christopher C. Goodnow

Nature Immunology · 2003 · 791 citations · 37 references

DOI

Concepts

References

37

Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein

Mark S. Anderson, Emily S. Venanzi, Ludger Klein et al. · Science · 2002 · 2.5K citations

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Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

Martha S. Jordan, Alina C. Boesteanu, Amy J. Reed et al. · Nature Immunology · 2001 · 1.6K citations

, , +15

Positional cloning of the APECED gene

Kentaro Nagamine, Pärt Peterson, Hamish S. Scott et al. · Nature Genetics · 1997 · 1.4K citations

, , +10

An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains

Johanna Aaltonen, Petra Björses, Jaakko Perheentupa et al. · Nature Genetics · 1997 · 1.2K citations

, , +14

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

Pamela S. Ohashi, Stephan Oehen, Kurt Buerki et al. · Cell · 1991 · 1.2K citations

, , +15