Deletion of Glutathione-S-Transferase M1 Reduces Azathioprine Metabolite Concentrations in Young Patients With Inflammatory Bowel Disease - Concepedia

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Deletion of Glutathione-S-Transferase M1 Reduces Azathioprine Metabolite Concentrations in Young Patients With Inflammatory Bowel Disease

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Citations

5

References

2013

Year

Gabriele Stocco, Eva Cuzzoni, Sara De Iudicibus, Raffaella Franca, Diego Favretto, Noelia Malusà, Margherita Londero, Gabriele Cont, Fiora Bartoli, Stefano Martelossi,

Journal of Clinical Gastroenterology

Abstract

This study describes the effect of candidate genetic polymorphisms in TPMT, ITPA, and GST-M1 on azathioprine pharmacokinetics in IBD patients, showing, for the first time, relevant effects of GST-M1 genotype on azathioprine metabolites concentration.

References

	Year	Citations

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