Concepedia

Tpmt Genotyping

TPMT Genotyping is a pharmacogenetic testing method that identifies genetic polymorphisms in the thiopurine S-methyltransferase (TPMT) gene to predict individual variations in thiopurine drug metabolism and guide personalized immunosuppressive therapy in transplantation.

265

Publications

15.8K

Citations

1.6K

Authors

547

Institutions

Publications per year

2017–2026

36

Variants

Tpmt Genotype Testing

Parents

Publications

265

Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy

Jean‐Frédéric Colombel, Nicolas Ferrari, Hervé Debuysère et al. · Gastroenterology · 2000 · 615 citations · Full text

, , +17

Clinical Pharmacogenetics Implementation Consortium Guidelines for Thiopurine Methyltransferase Genotype and Thiopurine Dosing

Mary V. Relling, E E Gardner, William J. Sandborn et al. · Clinical Pharmacology & Therapeutics · 2011 · 573 citations · Full text

, , +17

Comprehensive analysis of thiopurine S-methyltransferase phenotype–genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants

Elke Schaeffeler, Christine Fischer, D. Brockmeier et al. · Pharmacogenetics · 2004 · 420 citations

, , +14

Preponderance of Thiopurine S-Methyltransferase Deficiency and Heterozygosity Among Patients Intolerant to Mercaptopurine or Azathioprine

William E. Evans, Yuen Yi Hon, Lisa Bomgaars et al. · Journal of Clinical Oncology · 2001 · 403 citations

, , +14

Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms*

Diane M. Otterness, Carol L. Szumlanski, Lynne Lennard et al. · Clinical Pharmacology & Therapeutics · 1997 · 393 citations

, , +14

1–5 of 265

Authors

1.6K

  1. SL
    Soo‐Youn Lee

    Samsung Medical Center, South Korea

    10 publications · 321 citations

    10

    h-index

  2. AM
    Anthony M. Marinaki

    St Thomas' Hospital, United Kingdom

    9 publications · 1K citations

    9

    h-index

  3. AA
    Azhar Ansari

    St Thomas' Hospital, United Kingdom

    8 publications · 962 citations

    8

    h-index

  4. JS
    Jeremy Sanderson

    King's College London, United Kingdom

    8 publications · 962 citations

    8

    h-index

  5. WE
    William E. Evans

    St. Jude Children's Research Hospital, United States

    7 publications · 1.6K citations

    7

    h-index

1–5 of 1.6K

Institutions

547

  1. Linköping University

    Linköping, Sweden

    12 h-index

    33 publications

    2.1K citations

  2. St. Jude Children's Research Hospital

    Memphis, United States

    10 h-index

    51 publications

    7.6K citations

  3. Samsung Medical Center

    Seoul, South Korea

    10 h-index

    65 publications

    2.2K citations

  4. Sungkyunkwan University

    Seoul, South Korea

    10 h-index

    58 publications

    1.9K citations

  5. GTx (United States)

    Memphis, United States

    7 h-index

    18 publications

    1.1K citations

  6. University of Manchester

    Manchester, United Kingdom

    7 h-index

    48 publications

    5K citations

  7. Mayo Clinic

    Rochester, United States

    7 h-index

    27 publications

    5.2K citations

  8. Rigshospitalet

    Copenhagen, Denmark

    7 h-index

    25 publications

    5.6K citations

1–8 of 547

Venues

  1. PubMed

    Repository · 19 publications · 520 citations

    13

    h-index

  2. Pharmacogenetics

    12 publications · 2K citations

    12

    h-index

  3. Clinical Pharmacology & Therapeutics

    CPT · 12 publications · 2K citations

    12

    h-index

  4. Alimentary Pharmacology & Therapeutics

    11 publications · 890 citations

    11

    h-index

  5. Therapeutic Drug Monitoring

    10 publications · 446 citations

    10

    h-index

1–5