Elke Schaeffeler

Reduced Paneth cell α-defensins in ileal Crohn's disease

Jan Wehkamp, Nita H. Salzman, Edith Porter et al. · Proceedings of the National Academy of Sciences · 2005 · 957 citations · Full text

A Chromosome 8 Gene-Cluster Polymorphism with Low Human Beta-Defensin 2 Gene Copy Number Predisposes to Crohn Disease of the Colon

Klaus Fellermann, Daniel E. Stange, Elke Schaeffeler et al. · The American Journal of Human Genetics · 2006 · 559 citations · Full text

Gene-cluster Polymorphism, Genetics, Pathogenesis +9

A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study

Jesse J. Swen, Cathelijne H. van der Wouden, Lisanne E. N. Manson et al. · The Lancet · 2023 · 462 citations · Full text

Drug Safety, Adverse Drug Reactions, Pharmacoepidemiology +9

Comprehensive analysis of thiopurine S-methyltransferase phenotype–genotype correlation in a large population of German-Caucasians and identification of novel TPMT variants

Elke Schaeffeler, Christine Fischer, D. Brockmeier et al. · Pharmacogenetics · 2004 · 417 citations

Genetics, Genetic Epidemiology, Human Polymorphism +19

High plasma pravastatin concentrations are associated with single nucleotide polymorphisms and haplotypes of organic anion transporting polypeptide-C (OATP-C, SLCO1B1)

Mikko Niemi, Elke Schaeffeler, Thomas Lang et al. · Pharmacogenetics · 2004 · 416 citations