Engineering liver tissue spheroids with inverted colloidal crystal scaffolds

Cell and Environment Interactions in Tumor Microregions: The Multicell Spheroid Model

Robert M. Sutherland · Science · 1988 · 1.8K citations

Medicine, Cancer Biology, Cell Biology +17

Method for generation of homogeneous multicellular tumor spheroids applicable to a wide variety of cell types

Jens M. Kelm, Nicholas Timmins, Catherine J. Brown et al. · Biotechnology and Bioengineering · 2003 · 916 citations

Life Sciences, Bioengineering, Cell Biology +13

High concordance of drug-induced human hepatotoxicity with in vitro cytotoxicity measured in a novel cell-based model using high content screening

Peter J. O’Brien, William Irwin, Dolores Diaz et al. · Archives of Toxicology · 2006 · 609 citations

Pharmacy, Pharmacology, Toxicology +16

A New Description of Cellular Quiescence

Hilary A. Coller, Liyun Sang, James M. Roberts · PLoS Biology · 2006 · 557 citations · Full text

Life Sciences, Biology, Cell Biology +17

Formation of multicellular spheroids composed of adult rat hepatocytes in dishes with positively charged surfaces and under other nonadherent environments

Norio Koide, Khosaku Sakaguchi, Yayoi Koide et al. · Experimental Cell Research · 1990 · 441 citations

Engineering, Bioengineering, Cell Biology +12