Concepedia

Spheroid Models

Spheroid Models is a three-dimensional in vitro cell culture system that recapitulates the structural and functional complexity of native tissues by promoting self-assembly of cells into spherical aggregates, thereby enabling more physiologically relevant modeling of disease processes compared to traditional two-dimensional monolayer cultures.

3.1K

Publications

173.5K

Citations

15.1K

Authors

3.3K

Institutions

Publications per year

2017–2026

1.4K

Variants

Spheroid Model

Parents

Publications

3.1K

Assembly of functionally integrated human forebrain spheroids

Fikri Birey, Jimena Andersen, Christopher D. Makinson et al. · Nature · 2017 · 1.3K citations · Full text

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The magnetic lead field theorem in the quasi-static approximation and its use for magnetoencephalography forward calculation in realistic volume conductors

Guido Nolte · Physics in Medicine and Biology · 2003 · 1.2K citations

, , +13

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

Michele Zanoni, Filippo Piccinini, Chiara Arienti et al. · Scientific Reports · 2016 · 1.1K citations · Full text

, , +16

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

Maria Vinci, Sharon Gowan, Frances Boxall et al. · BMC Biology · 2012 · 1K citations · Full text

, , +17

Aggregation of human mesenchymal stromal cells (MSCs) into 3D spheroids enhances their antiinflammatory properties

Thomas J. Bartosh, Joni Ylöstalo, Arezoo Mohammadipoor et al. · Proceedings of the National Academy of Sciences · 2010 · 968 citations

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1–5 of 3.1K

Authors

15.1K

  1. MI
    Manfred Infanger

    Aarhus University, Denmark

    22 publications · 1.2K citations

    21

    h-index

  2. DG
    Daniela Grimm

    Aarhus University, Denmark

    26 publications · 1.2K citations

    21

    h-index

  3. JB
    Johann Bauer

    Paracelsus Medical University, Austria

    20 publications · 1.1K citations

    19

    h-index

  4. RM
    Robert M. Sutherland

    University of Rochester, United States

    19 publications · 1.9K citations

    18

    h-index

  5. JP
    James P. Freyer

    Los Alamos National Laboratory, United States

    18 publications · 1.5K citations

    17

    h-index

1–5 of 15.1K

Institutions

3.3K

  1. Centre National de la Recherche Scientifique

    Paris, France

    43 h-index

    419 publications

    28.3K citations

  2. Harvard University

    Cambridge, United States

    33 h-index

    129 publications

    17.4K citations

  3. Inserm

    Paris, France

    31 h-index

    239 publications

    15.5K citations

  4. Karolinska Institutet

    Stockholm, Sweden

    27 h-index

    152 publications

    19.2K citations

  5. National Taiwan University

    Taipei, Taiwan

    25 h-index

    97 publications

    6.3K citations

  6. University of Michigan

    Ann Arbor, United States

    24 h-index

    108 publications

    15.7K citations

  7. Heidelberg University

    Heidelberg, Germany

    23 h-index

    118 publications

    11.4K citations

  8. Massachusetts Institute of Technology

    Cambridge, United States

    23 h-index

    65 publications

    4.7K citations

1–8 of 3.3K

Venues

  1. Scientific Reports

    124 publications · 9.3K citations

    51

    h-index

  2. PLoS ONE

    93 publications · 6.4K citations

    48

    h-index

  3. Biomaterials

    46 publications · 5.1K citations

    41

    h-index

  4. PubMed

    Repository · 110 publications · 6.5K citations

    40

    h-index

  5. Lab on a Chip

    48 publications · 3.7K citations

    33

    h-index

1–5