Concepedia

IL2RA/CD25 Gene Polymorphisms: Uneven Association with Multiple Sclerosis (MS) and Type 1 Diabetes (T1D)

Antonio Alcina, Marı́a Fedetz, Dorothy Ndagire, Óscar Fernández, Laura Leyva, Miguel Guerrero, María M. Abad‐Grau, Carmen Arnal, Concepción Delgado, Miguel Lucas,

PLoS ONE · 2009 · 78 citations · 27 references

DOIFull text

Open access

Abstract

These findings confirm and extend the association of this gene with MS and reveal a genetic heterogeneity of the associated polymorphisms and risk alleles between MS and T1D suggesting different immunopathological roles of IL2RA in these two diseases.

References

27

Haploview: analysis and visualization of LD and haplotype maps

Jeffrey C. Barrett, Ben Fry, Julian Maller et al. · Bioinformatics · 2004 · 14.5K citations · Full text

New diagnostic criteria for multiple sclerosis: Guidelines for research protocols

Charles M. Poser, Donald W. Paty, Labe C. Scheinberg et al. · Annals of Neurology · 1983 · 7.4K citations

, , +5

Risk Alleles for Multiple Sclerosis Identified by a Genomewide Study

New England Journal of Medicine · 2007 · 1.7K citations

A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis

Ann B. Begovich, Victoria Carlton, Lee Honigberg et al. · The American Journal of Human Genetics · 2004 · 1.5K citations · Full text

, , +13

A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes

Nunzio Bottini, Lucia Musumeci, Andrés Alonso et al. · Nature Genetics · 2004 · 1.4K citations · Full text

, , +9