Lee Honigberg

The Bruton tyrosine kinase inhibitor PCI-32765 blocks B-cell activation and is efficacious in models of autoimmune disease and B-cell malignancy

Lee Honigberg, Ashley M. Smith, Mint Sirisawad et al. · Proceedings of the National Academy of Sciences · 2010 · 1.5K citations · Full text

Life Sciences, Immunology, Pharmacology +17

A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis

Ann B. Begovich, Victoria Carlton, Lee Honigberg et al. · The American Journal of Human Genetics · 2004 · 1.5K citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Discovery of Selective Irreversible Inhibitors for Bruton’s Tyrosine Kinase

Zhengying Pan, Heleen Scheerens, Shyr‐Jiann Li et al. · ChemMedChem · 2006 · 675 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Effect of selective LRRK2 kinase inhibition on nonhuman primate lung

Reina N. Fuji, Michael Flagella, Miriam Baca et al. · Science Translational Medicine · 2015 · 370 citations

Pharmacy, Pharmacology, Toxicology +13

Efficacy and Safety of Lampalizumab for Geographic Atrophy Due to Age-Related Macular Degeneration

Frank G. Holz, Srinivas R. Sadda, Brandon Busbee et al. · JAMA Ophthalmology · 2018 · 351 citations · Full text

Medicine, Neurology, Ophthalmology +17