Concepedia

Methods for the design and analysis of oligodeoxynucleotide-based DNA (cytosine-5) methyltransferase inhibitors

Jarrod Clark, Taras Shevchuk, Mark R Kho, Steven S. Smith

Analytical Biochemistry · 2003 · 13 citations · 31 references

DOI

Concepts

References

31

Hhal methyltransferase flips its target base out of the DNA helix

Saulius Klimašauskas, Sanjay Kumar, Richard J. Roberts et al. · Cell · 1994 · 945 citations

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On the mechanism of inhibition of DNA-cytosine methyltransferases by cytosine analogs

Daniel V. Santi, Charles Garrett, Philip J. Barr · Cell · 1983 · 401 citations

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Cytidine Deaminase. The 2·3 Å Crystal Structure of an Enzyme: Transition-state Analog Complex

Laurie Betts, Shibin Xiang, Steven A. Short et al. · Journal of Molecular Biology · 1994 · 382 citations

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The crystal structure of Haelll methyltransferase covalently complexed to DNA: An extrahelical cytosine and rearranged base pairing

Karin M. Reinisch, Lin Chen, Gregory L. Verdine et al. · Cell · 1995 · 366 citations · Full text

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Zebularine: A Novel DNA Methylation Inhibitor that Forms a Covalent Complex with DNA Methyltransferases

Lei Zhou, Xiaodong Cheng, Bernard A. Connolly et al. · Journal of Molecular Biology · 2002 · 363 citations · Full text

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