Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme

Masamichi Muramatsu, Kazuo Kinoshita, Sidonia Fagarasan, +3

Cell

Natural SciencesGeneticsRna BiologyMolecular BiologyGene Editing +5

Megabase Chromatin Domains Involved in DNA Double-Strand Breaks in Vivo

Emmy P. Rogakou, Chye Boon, Christophe E. Redon, +1

The Journal of Cell Biology

Megabase ChromatinDna DamageGeneticsRadiation EffectRadiation Exposure +20

Activation-Induced Cytidine Deaminase (AID) Deficiency Causes the Autosomal Recessive Form of the Hyper-IgM Syndrome (HIGM2)

Patrick Revy, Taro Muto, Yves Lévy, +18

Cell

Mendelian DisorderAutoimmune DiseaseGenetic DisorderGeneticsImmunology +6

A role for Saccharomyces cerevisiae histone H2A in DNA repair

Jessica A. Downs, Noel F. Lowndes, Stephen P. Jackson

Nature

Histone ModificationsChromatinGenome InstabilityChromatin RemodelingNatural Sciences +7

Binding of Chromatin-Modifying Activities to Phosphorylated Histone H2A at DNA Damage Sites

Jessica A. Downs, Stéphane Allard, Olivier Jobin‐Robitaille, +6

Molecular Cell

Histone ModificationsChromatinGenome InstabilityChromatin-modifying ActivitiesDna Damage +13

Distribution and Dynamics of Chromatin Modification Induced by a Defined DNA Double-Strand Break

Robert Shroff, Ayelet Arbel‐Eden, Duane R. Pilch, +5

Current Biology

ChromatinGenome InstabilityDna DamageChromatin StructureChromatin Remodeling +12

AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching

Simone Petersen, Rafael Casellas, Bernardo Reina‐San‐Martin, +13

Nature

Genetic DisorderNbs1/γ-h2ax Focus FormationGeneticsClass SwitchingMolecular Biology +4

Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome

Gangning Liang, Joy Lin, Vivian Wei, +8

Proceedings of the National Academy of Sciences

Apoptotic Phosphorylation of Histone H2B Is Mediated by Mammalian Sterile Twenty Kinase

Wang L. Cheung, Kozo Ajiro, Kumiko Samejima, +7

Cell

ChromatinSignal TransductionChromatin StructureHistone H2b IsChromatin Remodeling +11

Caspase-mediated activation and induction of apoptosis by the mammalian Ste20-like kinase Mst1

Jonathan D. Graves

The EMBO Journal

Caspase-mediated ActivationSignal TransductionSignaling PathwayCell RegulationReceptor Tyrosine Kinase +8