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Identification of a series of substituted 2-piperazinyl-5-pyrimidylhydroxamic acids as potent histone deacetylase inhibitors

Patrick Angibaud, Kristof Van Emelen, Laurence Decrane, Sven Van Brandt, Peter ten Holte, Isabelle Pilatte, Bruno Roux, Virginie Poncelet, David Speybrouck, Laurence Quéguiner,

Bioorganic & Medicinal Chemistry Letters · 2009 · 18 citations · 8 references

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Structures of a histone deacetylase homologue bound to the TSA and SAHA inhibitors

Michael S. Finnin, Jill R. Donigian, Alona Cohen et al. · Nature · 1999 · 1.7K citations

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Role of Class I and Class II histone deacetylases in carcinoma cells using siRNA

Keith B. Glaser, Junling Li, Michael J. Staver et al. · Biochemical and Biophysical Research Communications · 2003 · 218 citations

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A new synthesis of α-arylglycines from aryl boronic acids

Nicos A. Petasis, Andrew Goodman, Ilia A. Zavialov · Tetrahedron · 1997 · 210 citations

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R306465 is a novel potent inhibitor of class I histone deacetylases with broad-spectrum antitumoral activity against solid and haematological malignancies

Janine Arts, Patrick Angibaud, Ann Mariën et al. · British Journal of Cancer · 2007 · 89 citations · Full text

Belinostat: a new broad acting antineoplastic histone deacetylase inhibitor

Peter Gimsing · Expert Opinion on Investigational Drugs · 2009 · 51 citations