Fibulin-3-mediated inhibition of epithelial-to-mesenchymal transition and self-renewal of ALDH+ lung cancer stem cells through IGF1R signaling

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

Sendurai A. Mani, Wenjun Guo, Mai-Jing Liao et al. · Cell · 2008 · 8.6K citations · Full text

Regenerative Medicine, Epithelial-mesenchymal Transition, Developmental Biology +9

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

Dominique Bonnet, John E. Dick · Nature Medicine · 1997 · 6.9K citations

Hematological Malignancy, Chromatin, Cell Division +10

ALDH1 Is a Marker of Normal and Malignant Human Mammary Stem Cells and a Predictor of Poor Clinical Outcome

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Lineage Plasticity, Breast Oncology, Medicine +9

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

Jeongwu Lee, Svetlana Kotliarova, Yuri Kotliarov et al. · Cancer Cell · 2006 · 2.3K citations · Full text

Embryonic Stem Cell, Developmental Biology, Medicine +10

The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

Ulrich F. Wellner, Jörg Schubert, Ulrike Burk et al. · Nature Cell Biology · 2009 · 1.7K citations

Medicine, Emt-activator Zeb1, Small Rna +5